Design, synthesis and antitumor activity of a novel FGFR2-selective degrader to overcome resistance of the FGFR2V564F gatekeeper mutation based on a pan-FGFR inhibitor

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journal：European Journal of Medicinal Chemistry

Authors：Zuli Hu; Qiangsheng Zhang; Zulong Li; Hongling Yang; Xin Chen; Qi Zhang; Tianqiong Yang; Xiaojie He; Qiang Feng; Jun He; Luoting Yu

Published date：2024-9-

DOI：10.1016/j.ejmech.2024.116612

PDF link：https://www.sciencedirect.com/sc ... 223523424004926/pdf

Article link：http://dx.doi.org/10.1016/j.ejmech.2024.116612

Article Source：Elsevier BV。

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[Elsevier] Design, synthesis and antitumor activity of a novel FGFR2-selective degrader to overcome resistance of the FGFR2V564F gatekeeper mutation based on a pan-FGFR inhibitor

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[Elsevier] Design, synthesis and antitumor activity of a novel FGFR2-selective degrader to overcome resistance of the FGFR2V564F gatekeeper mutation based on a pan-FGFR inhibitor Copy

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[Elsevier] Design, synthesis and antitumor activity of a novel FGFR2-selective degrader to overcome resistance of the FGFR2V564F gatekeeper mutation based on a pan-FGFR inhibitor