Fragment-Based Drug Discovery Targeting Inhibitor of Apoptosis Proteins: Discovery of a Non-Alanine Lead Series with Dual Activity Against cIAP1 and XIAP

Post time 2024-6-15 06:47:37

journal：Journal of Medicinal Chemistry

Authors：Gianni Chessari; Ildiko M. Buck; James E. H. Day; Philip J. Day; Aman Iqbal; Christopher N. Johnson; Edward J. Lewis; Vanessa Martins; Darcey Miller; Michael Reader; David C. Rees; Sharna J. Rich; Emiliano Tamanini; Marc Vitorino; George A. Ward; Pamela A. Williams; Glyn Williams; Nicola E. Wilsher; Alison J.-A. Woolford

Published date：2015-8-27

DOI：10.1021/acs.jmedchem.5b00706

PDF link：https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b00706

Article link：http://dx.doi.org/10.1021/acs.jmedchem.5b00706

Article Source：American Chemical Society (ACS)。

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[ACS] Fragment-Based Drug Discovery Targeting Inhibitor of Apoptosis Proteins: Discovery of a Non-Alanine Lead Series with Dual Activity Against cIAP1 and XIAP

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[ACS] Fragment-Based Drug Discovery Targeting Inhibitor of Apoptosis Proteins: Discovery of a Non-Alanine Lead Series with Dual Activity Against cIAP1 and XIAP