Design, synthesis, and biological evaluation of novel quinoline derivatives as small molecule mutant EGFR inhibitors targeting resistance in NSCLC: In vitro screening and ADME predictions

Post time 2024-6-11 03:17:46

journal：European Journal of Medicinal Chemistry

Authors：Ramakant A. Kardile; Aniket P. Sarkate; Deepak K. Lokwani; Shailee V. Tiwari; Rajaram Azad; Shankar R. Thopate

Published date：2023-1-

DOI：10.1016/j.ejmech.2022.114889

PDF link：https://www.sciencedirect.com/sc ... 223523422007917/pdf

Article link：http://dx.doi.org/10.1016/j.ejmech.2022.114889

Article Source：Elsevier BV。

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[Elsevier] Design, synthesis, and biological evaluation of novel quinoline derivatives as small molecule mutant EGFR inhibitors targeting resistance in NSCLC: In vitro screening and ADME predictions

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[Elsevier] Design, synthesis, and biological evaluation of novel quinoline derivatives as small molecule mutant EGFR inhibitors targeting resistance in NSCLC: In vitro screening and ADME predictions