Discovery of a Potent, Cooperative, and Selective SOS1 PROTAC ZZ151 with In Vivo Antitumor Efficacy in KRAS-Mutant Cancers

Post time 2023-3-14 11:05:00

journal：Journal of Medicinal Chemistry

Authors：Zehui Zhou; Guizhen Zhou; Chuan Zhou; Zisheng Fan; Rongrong Cui; Yupeng Li; Rui Li; Yuejiao Gu; Huajie Li; Zhiming Ge; Xiaojia Cai; Bing Jiang; Dan Wang; Mingyue Zheng; Tianfeng Xu; Sulin Zhang

Published date：--

DOI：10.1021/acs.jmedchem.3c00075

Article link：http://dx.doi.org/10.1021/acs.jmedchem.3c00075

Article Source：American Chemical Society (ACS)。

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Post time 2023-3-14 11:05:01

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[ACS] Discovery of a Potent, Cooperative, and Selective SOS1 PROTAC ZZ151 with In Vivo Antitumor Efficacy in KRAS-Mutant Cancers

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